Do ACE inhibitors modulate atherosclerosis?

Do ACE inhibitors decrease mortality in patients with hypertension?

Monocyte mayhem: do subtypes modulate distinct atherosclerosis phenotypes?

Atherosclerosis is a lipoprotein disorder with inflammatory, vascular, and hemodynamic determinants. Total white blood cell count and subpopulations including granulocytes, monocytes, T cells, and bone marrow-derived precursors have been implicated in atherosclerotic cardiovascular disease (CVD).1,2 Although these associations may inform biological processes, they have not, to date, permitted s...

ACE, ACE inhibitors, and other JNK.

The renin-angiotensin system (RAS) plays a pivotal role in the regulation of blood pressure, volume homeostasis, vascular function, and cell growth. In what is considered the classic RAS, renin is released from juxtaglomerular cells of the kidney into the circulation where it converts angiotensinogen from the liver to angiotensin I. Angiotensin I is subsequently hydrolyzed by a peptidyl dipepti...

Angiotensin converting enzyme ( ACE ) inhibitors modulate CRBP 1 and adiponectin expression in adipocytes via the ACE - dependent signaling cascade

Institute for Vascular Signalling (KK, CG, CT, IF), and Department of Internal Medicine III (SF), Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, and Department of Hematology and Oncology (W-KH), University Hospital Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany. Molecular Pharmacology Fast Forward. Published on December 29, 2008 as doi:10.1124/mol....

ACE inhibitors and anaesthesia.

During the last decade, two angiotensin converting enzyme (ACE) inhibitors, captopril and enalapril, have become accepted into clinical practice and are regarded as effective treatments for hypertension and congestive cardiac failure.' A third agent, lisinopril, had recently become available and others are likely to be introduced in the near future. It is clear, therefore, that more patients, w...